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COVER STORY
2
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CAS
EDITORIAL
4
Does the REACH 2018 registration deadline affect you?
C. Musset
ANALYTICAL TECHNOLOGIES
6
Recent evolution of flow-modulation comprehensive gas
chromatography within the context of mass spectrometry
hyphenation
F. A. Franchina, G. Purcaro, M. Maimone, P. Q. Tranchida, L.
Mondello
12
New vistas in mass spectrometry for sequence analysis of natural
and synthetic biodegradable macromolecules
M. Kowalczuk
17
Polycyclic aromatic hydrocarbon determination (PAHs) transported
by storm water drainage in the Pelotas region and its levels in São
Gonçalo Channel
M. S. Hall, G. O. Montenegro, G. R. Betemps, B. S. Vaz,
P. J. F. Sanches
23 Relative cost-effectiveness modeling to understand the value of
preparative chiral separations in pharmaceutical R&D
J. P. Kiplinger
COMPANY PROFILE
27
AAIPharma Services Corporation and Cambridge Major
Laboratories, Inc. are now Alcami
Alcami
PROCESS OPTIMIZATION
28 Making design of experiments work in industry:
A case study in optimising an existing chemical process
M. Moore, P. Kay
33
NEWS
CATALYSIS AND BIOCATALYSIS
42 Teach new tricks for an old dog: cheap and abundant iron
complexes for new catalytic transformations
L. Mengozzi, P. Giorgio Cozzi, A. Gualandi
46 Adsorption of lead (II) on mesoporous carbon CMK-3 from single,
binary and ternary metal aqueous solution
R. Bouri, L. Cherif, R. Denoyel
52 Bioremediation techniques for naproxen and carbamazepine
elimination - Toxicity evaluation test
M. C. Molina, , N. González Benítez, R. Simarro, L.F. Bautista, C.
Vargas, J.P. García-Cambero, E.M. Díaz, M. Arrayás,
M. A. Quijano
REGULATION
56 Test data in REACH: requirements and developments
Examining developments in REACH and their impact
on information requirements
P. B. Walters
60
Will REACH still be there after 2018?
E. Annys
63
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International Journalof
FineChemicals,AppliedChemistryandBiotechnology
ISSN0392-839XCHOGDS
Poste ItalianeSpa -Sped. inAbb.Postale -D.L.353/2003 (conv. InL.27/02/2004n.46) -art.1comma1 -DCBMilano •ChimicaOggi /ChemistryToday -vol34(2) -March/April2016 •PublishedbyTeknoScienzeSrl
Chimica Oggi - Chemistry Today
vol. 34(2) March/April 2016
Chimica Oggi - Chemistry Today
is a peer-reviewed journal devoted to fine
chemistry, pharmaceuticals and biotechnology addressed to a readership
belonging to the industry. An
impact factor of 0,390
is listed in the 2014 Journal
Citation Reports (ISI Web of Knowledge).
CONTENTS
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