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Efficient process intensification of fine chemical production
A new classification tool for flow chemistry technologies

AXEL LEXMOND, MARK ROELANDS, MARTIJN P. DE GRAAFF*, JEAN-MARIE BASSETT
*Corresponding author
TNO Science and Industry, P.O. Box 6012, Delft, NL- 2600 JA, The Netherlands

Abstract

The fine chemicals and pharmaceuticals industryneeds to innovate to beat international competition andresolve environmental issues. Process intensification by flowchemistry is the most promising route for this change, as itcan reduce raw material and energy consumption, wasteproduction, lead time and time-to-market. However, the sheernumber of new technologies that are considered, appearsto hinder its progress. Dutch contract research organizationTNO has constructed a tool that can help in selecting newtechnologies, ensuring that only a few new technologieswill have to be implemented. This tool can be used fordetailing the existing roadmap, aiming to accelerate theimplementation of flow chemistry in the fine chemicals sector.