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RTC SERVICES

• Project Design-
• Regulatory Testing
• Bioanalytical services

AREAS OF ACTIVITY

Metabolism and Toxicokinetic

Method set-up and validation

Sample analysis 

Genotoxicity

In vitro tests 

• Bacterial Mutation Assay (OECD 471)
• in vitro Mammalian Cells  Micronucleus Test (OECD 487)

The need of additional in vitro tests is evaluated in case of positive or equivocal results

In vivo follow-up tests 

• Mammalian Erythrocyte Micronucleus test (OECD 474)
• in vivo Mammalian Alkaline Comet Assay (OECD 489)

RTC has a broad experience with integration of the micronucleus en ... ...