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- 03/14/2017

Novartis gets FDA approval for its drug as first-line treatment for breast cancer

Pharma Horizon

The U.S. Food and Drug Administration had approved Novartis’s experimental drug, kisqali, as a first-line treatment for a type of breast cancer in postmenopausal women, in combination with another breast cancer drug.

The approval is based on a late-stage data: more than half of patients taking kisqali plus letrozole remained alive, the company said.

Kisqali, an oral drug, helps in slowing down the progression of cancer by preventing two proteins called cyclin-dependent kinase 4 and 6 (CDK4/6). These proteins when over-activated can enable cancer cells to grow and divide too quickly.

Kisqali, by targeting CDK4/6, helps in ensuring that cancer cells do not continue to replicate uncontrollably.

Breast cancer is the second most common cancer in American women. The American Cancer Society estimates that more than 250,000 women will be diagnosed with invasive breast cancer in 2017.

Source: The Daily Mail




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