PANEL DISCUSSION ON HPAPIs
Innovation has been the driving force of the pharmaceutical industry since its very beginnings. For more than a century, the pharmaceutical industry offered a customized response to most diseases and even discomforts related to our health.
A driver of innovation is the search for increasingly targeted efficacy and the reduction of undesirable effects.
Initially, the potential activity of millions of molecules was tested empirically. This approach, still practiced today, has led to major advances.
For several decades, the increasingly precise knowledge of the chemical and biochemical mechanisms of our body as well as the capacity to model new potentially active molecules offered by Artificial Intelligence, have led research to propose increasingly complex active targets which are adapted to the mechanism of the living.
The synthesis of small and large molecules (peptides and antibodies) required the development of new technologies in chemical synthesis or in purification or isolation steps. However, the biggest breakthrough is related to the t ...