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EDITORIAL
2018 was a pivotal year for oligonucleotide therapeutics
K. L. Ackley
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OLIGONUCLEOTIDES & PEPTIDES
Oral peptide therapeutics: Getting easier to swallow?
Bruce H. Morimoto
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OLIGONUCLEOTIDES & PEPTIDES
New manufacturing process to produce highly uniform resins with excellent performances in Solid Phase Peptide Synthesis
O. Al Musaimi, S. Serban, Y. E. Jad, Z. Ma, A. Kumar, C. Ji, B. G. De La Torre , N. R. East, A. Basso, F. Albericio
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OLIGONUCLEOTIDES & PEPTIDES
Development of an efficient purification method for a peptide pharmaceutical – Optimisation of HPLC separation and considerations for scaling up to production scale in case of the GLP-1 receptor agonist liraglutide
A. Kremser, C. A. White
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OLIGONUCLEOTIDES & PEPTIDES
Therapeutic peptides – What makes them different?
F. O. Gombert
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A WORD WITH
Elisabetta Bianchi, Director Peptide Chemistry – IRBM S.p.A.
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OLIGONUCLEOTIDES & PEPTIDES
Exploring methods for a difficult coupling
C. N. Ramos-Colon, D. Martinez, A. Kennedy, J. P. Cain
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OLIGONUCLEOTIDES & PEPTIDES
Short arginine analogs: peptide synthesis and prediction of biological effects – Efficient synthesis of peptides containing short analogs of arginine and stability evaluation with docking. Prediction of biological effects of short arginine analogs using computational methods.
T. A. Dzimbova, P. Henklein, T. Bruckdorfer, R. M. Maier, M. W. Weishaupt, T. I. Pajpanova
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COMPANY PROFILE
CordenPharma Expands Peptide Capacity to Support Recent Market Trends
M. Giraud
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OLIGONUCLEOTIDES & PEPTIDES
Improving crude product quality for complex synthetic peptides
M. W. Pennington
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OLIGONUCLEOTIDES & PEPTIDES
Aspects of greening peptide chemistry within the pharmaceutical manufacturing industry
J. H. Rasmussen, J. Pawlas, O. Ludemann-Hombourger, E. D. Rekai
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OLIGONUCLEOTIDES & PEPTIDES
Tips and tricks in the preparation of anti-peptide antibodies
E. F. Kolesanova
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OLIGONUCLEOTIDES & PEPTIDES
Technical and regulatory strategies for synthetic peptides
J. R. Ferguson, M. O. Frederick, M. E. Kopach, K. D. Seibert, M. A. Strege
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PANEL DISCUSSION ON PEPTIDES
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PEPTIDES
Panel Discussion on Peptides – Commentary article
K. L. Ackley
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PANEL DISCUSSION ON OLIGONUCLEOTIDES
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OLIGONUCLEOTIDES & PEPTIDES
The DNA-Based Drug BC 007 neutralizes agonistically acting autoantibodies directed against G protein–coupled receptors – Successful mode of action demonstrated in clinical phase 1 trial
J. Müller, A. Haberland, G. Wallukat, N. P. Becker, K. Wenzel, P. Göttel, S. Schulze-Rothe, I. Schimke, T. Yilmaz, A. Abay, G. Golor, M. Grossmann, A. Sinn, A. Wallukat, A. S. Hönicke, H. Davideit, S. Becker
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OLIGONUCLEOTIDES & PEPTIDES
Antisense oligonucleotide-mediated DNM2 targeting in centronuclear myopathies – From preclinical proof of concept towards clinical trials
B. S. Cowling, S. Guo
