Register  /  Login               
Print this article

Elisabetta Bianchi, Director Peptide Chemistry – IRBM S.p.A.

Keywords:

e-version image

Click HERE to download the PDF version




WHAT ARE THE DRUG CANDIDATES THAT IRBM IS CURRENTLY DEVELOPING?

Our peptide chemistry team has extensive expertise in peptide and macrocyclic drug discovery in various therapeutic areas and a track record in the clinic. Drug candidates that we are currently developing include peptides that incorporate non-proteinogenic amino acids and peptide conjugates to various pharmacokinetic enhancing moieties such as fatty acids, cholesterol and polymers that enable prolonged in vivo exposure due to reduced renal filtration and proteolysis. Much emphasis is on the stabilization of our leads by metabolite identification from high resolution mass spectrometry studies on in vitro and in vivo samples. Our drug candidates also include a very important class of molecules specifically peptide macrocycles of ...




About us



Teknoscienze publisher
& Event Organizer

Viale Brianza, 22
20127 - Milano - Italy

info@teknoscienze.com
Tel. +39 02 26809375