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High fiber cane: Pathway to a novel xylooligosaccharide prebiotic and human health

corresponding

SANDRA SAVILLE1, BRADLEY A. SAVILLE1,2*
*Corresponding Author
1. Prenexus Health, Gilbert, USA
2. University of Toronto, Department of Chemical Engineering and Applied Chemistry, Toronto, Canada

Abstract

Xylooligosaccharides are recognized for their ability to selectively feed beneficial bacteria, and provide health benefits at a comparatively low dose of 1 to 4 grams per day. Although xylooligosaccharides have been commercially available for over 30 years, constraints in supply from traditional sources have limited their commercial use. The xylan present in high fiber cane represents an excellent new source of xylooligosaccharides. A novel hot water extraction process has been developed to extract these oligosaccharides, avoiding the use of enzymes and acids required for conventional processes. The hot water extraction process, coupled with strategic downstream purification processes, produce a product rich in xylooligosaccharides and other fiber-derived oligosaccharides. These oligosaccharides have a degree of polymerization mainly from 3 – 12, higher than some other sources, yet still effectively utilized by bifidobacteria within the digestive tract.


INTRODUCTION

Prebiotics such as xylooligosaccharides are gaining recognition for their ability to selectively feed beneficial bacteria and provide potential health benefits. Although xylooligosaccharides have been commercially available for over 30 years, their availability from traditional sources has been limited. In this article, we describe the properties and health benefits of xylooligosaccharides (XOS), and describe a novel pathway for their production from high fiber varieties of cane.

INTRODUCTION TO XYLOOLIGOSACCHARIDES (XOS) - IMPACTS ON THE MICROBIOME AND HEALTH

Prebiotics are increasingly being added to foods and beverages, and consumed as supplements, as consumers seek to modulate their microbiome and accrue health benefits. Among prebiotics, xylooligosaccharides are gaining attention due to their ability to provide health benefits at doses in the range of 1 – 4 g/d (1), substantially lower than the effective dose for other prebiotics (typically fructans).  

In particular, xylooligosaccharides are recognized for their ability to selectively fe ...




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