Latest publications in powder technologies and processing
In order to give up to date information to our readers on how technologies are being continuously implemented in fields such as the production and handling of active powders, we thought that the publication of a list of abstracts of the most recent and interesting peer reviewed papers found in Pubmed could be useful. We invite our readers to read each article in order to deepen the studies and methods developed by companies to manufacture formulations, control their quality and investigate their performance and effects.
Downstream processing of polymer-based amorphous solid dispersions to generate tablet formulations.
Démuth B, Nagy ZK, Balogh A, Vigh T, Marosi G, Verreck G, Van Assche I, Brewster ME, Int J Pharm., 486(1-2), 268-286 (2015); doi: 10.1016/j.ijpharm.2015.03.053.
ABSTRACT: Application of amorphous solid dispersions (ASDs) is considered one of the most promising approaches to increase the dissolution rate and extent of bioavailability of poorly water soluble drugs. Such intervention is often required for new drug candidates in that enablement, bioavailability is not sufficient to generate a useful pr ...