Latest publications in powder technologies and processing
In order to give up to date information to our readers on how technologies are being continuously implemented in a so important field such as the handling of pharmaceuticals powders, we thought that the publication of a list of the abstracts of the most recent and interesting peer reviewed papers found in Pubmed, could be useful. We invite our readers to read each article in order to deepen the studies and methods developed by companies to manufacture formulations and investigate their performance and effects. Comments and in-depth analysis are welcome.
MICRONIZATION OF THE PHARMACEUTICALLY ACTIVE AGENT GENIPIN BY AN ANTISOLVENT PRECIPITATION PROCESS
Zhao, X., Song, K., Wang, S., Zu, Y., Li, N. and Yu, X., Chem. Eng. Technol., 36, 33–42 (2013). doi: 10.1002/ceat.201200036
Due to its low water solubility and slow dissolution rate, genipin was micronized by an antisolvent precipitation process using ethanol as solvent and n-hexane as antisolvent. The effects of various experimental parameters on the mean particle size (MPS) of micronized genipin were investigated. By analysis of variance, only t ...