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RTC – TOXICOLOGICAL SERVICES FOR NOVEL FOOD, FOOD ADDITIVES AND FOOD INGREDIENTS – Research Toxicology Centre

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RTC SERVICES

  • Project Design-
  • Regulatory Testing
  • Bioanalytical services

AREAS OF ACTIVITY

Metabolism and Toxicokinetic

Method set-up and validation

Sample analysis 

Genotoxicity

In vitro tests 

  • Bacterial Mutation Assay (OECD 471)
  • in vitro Mammalian Cells  Micronucleus Test (OECD 487)

The need of additional in vitro tests is evaluated in case of positive or equivocal results

In vivo follow-up tests 

  • Mammalian Erythrocyte Micronucleus test (OECD 474)
  • in vivo Mammalian Alkaline Comet Assay (OECD 489)

RTC has a broad experience with integration of the micronucleus en ... ...




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