The Promise of PeptideTherapeutics
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Despite exceptional specificity, high potency, and low toxicity, common misconceptions continue to limit the potential of peptide-based therapeutics.
THE FACTS TELL A DIFFERENT STORY
Misconception: Peptides elicit undesired antibody response
Fact: Small-medium synthetic peptides are poor immunogens
Misconception: Peptide therapeutics offer poor pharmacokinetics/ serum stability
Fact: High in vivo concentrations reach target receptors within 60 seconds
Misconception: Limited oral bioavailability makes peptide drugs undesirable
Fact: Advances in subcutaneous and intranasal drug delivery offer incre ... ...