Abstract

Silicones are macromolecules constituted by a flexible but structurally solid backbone of silica and oxygen. Silicones are highly exploited in personal care products because of their properties: they are de facto inert compounds able to give to cosmetics formulation an easily spreadable and silky texture. Their physiological inertness is particularly beneficial in terms of cosmetic use and skin chemical compatibility. Silicones and their derivatives are in fact used, for instance, as emollients, humectants, emulsifiers, antifoaming, viscosity-controlling agents, antistatic and binding agents, etc.

As above-mentioned, silicones can be found in very different personal care products. For this reason, specific criteria of selection were necessarily applied in this “insights “section to narrow done the potential innovations. This literature review is therefore organized into two macro-areas:

1) Silicones in skin care. In the first study, a thiolated silicone oils was inserted in protective creams and their impact on efficacy was assessed. The second abstract discusses the development of a highly persistent silicone-based sprayable emulsion for the treatment of skin infections. Finally, the third study reports self-healing antibacterial injectable dual-network silica-based nanocomposite hydrogel scaffolds that significantly enhance the diabetic wound healing/skin tissue formation.
2) Silicones in hair care. The first study investigated the delivery to hair follicles of thiolated and PEGylated silica nanoparticle, while the second abstract is based on the comparison, after follicular unit extraction hair transplantation, between a novel silicone gel wound dressing and the bacitracin.

1 SILICONES IN SKIN CARE

Scientific online resources as Pubmed and Google Scholar were used to retrieve articles of interest. To screen for the most advanced researches, articles were selected between the years 2020 and 2022 with the following keywords: silicon, silicone, skin.

Thiolated Silicone Oils as New Components of Protective Creams in the Prevention of Skin Diseases

Agnieszka Kulawik-Pióro1, Anna K Drabczyk1, Joanna Kruk2, Magdalena Wróblewska3, Katarzyna Winnicka3,
Justyna Tchórzewska4

Affiliations:

1. Department of Chemical Engineering and Technology, Institute of Organic Chemistry and Technology, Cracow University of Technology, Warszawska 24, 31-155 Kraków, Poland.
2. Department of Engineering and Machinery for Food Industry, Faculty of Food Technology, University of Agriculture in Kraków, Balicka 122, 30-149 Kraków, Poland.
3. Department of Pharmaceutical Technology, Faculty of Pharmacy with the Division of Laboratory Medicine, Medical Univ ...
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