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Maximizing returns through re-formulation: re-formulation strategies for old molecules

corresponding

MIGUEL GIMENO SIERRA*, BORJANA LUBURA
Jesmond Bioscience GmbH, Vienna, Austria

Abstract

One of the reasons for the development of new and improved formulations in the sector of agro- and biocidal products is the emergence of resistance of various weeds and insects towards older molecules. In order to overcome this resistance as well as certain physic-chemical incompatibilities and to improve the activity and decrease the toxicity, improved chemical formulations were developed. This paper focuses on one main example which is a summary of the efficacy study for an insecticidal product based on actives, Pyrethrum (PYR) and Piperonyl butoxyde (PBO) by applying the microencapsulation technology


INTRODUCTION

There are three groups of chemical molecules which are dominant in the area of crop protection which are grouped in various ways according to their activity, mechanism of action, timing and method of application, chemical family or their selectivity. They belong to herbicides which are substances that kill or inhibit growth of weeds, insecticides which are substances that kill arthropod pests, and which are very important in combating human and animal diseases and fungicides which are substances that destroy or prevent the growth of pathogenic fungi. All three belong to pesticides. Some of them are designed to control a broad range of weeds or insect pests, while others are designed to control only selected types of the same. In this regard, proper timing will lead to adequate weed or insect control, while improper application timing may result in a failure to control either of them adequately. 

The table 1 summarizes some of the commonly used herbicides.

In the middle of the 19th century an insecticidal powder derived from dried flower heads of the genus Pyrethrum (Chrysanthemum) was introduced from Africa to central Europe. T ...




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