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Psoriatic in vitro epidermis A human tissue culture model for testing cosmetical and medical skin care products

CLAAS RÜFFER

Dermatest GmbH, Engelstrasse 37, Münster, 48143, Germany

Abstract

The very complex nature of psoriasis pathogenesis and its course of disease mean an outstanding challenge for the development of reliable biological in vitro systems. Recent progress in psoriasisresearch has led to the development of new REACH-compatible in vitro Epidermis Models. Dermatest GmbH utilizes a cytokine-transformed in vitro 3D model that mirrors characteristic epidermal aspects of psoriasis. This model can be used to test topical treatments and skin care products in their effectiveness to restore lost skin barrier properties.


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