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Review of atopic dermatitis:
epidemiological, physiopathological and therapeutic aspects

corresponding

SAYAG MICHELE*, ERIC JOURDAN
*Corresponding author
MD, Medical Strategy Director, Laboratoire Bioderma, 75 cours Albert Thomas, 69447 Lyon Cedex 03, France

KEYWORDS: Atopic dermatitis, epidemiology, physiopathology, treatment.
ABSTRACT:
Atopic dermatitis (AD) is one of the most common inflammatory skin disorders. Its prevalence has doubled in the past 20 years. It is a combination of genetic factors and environmental factors. The current recommendations rely on an early first-line essential treatment of eczema lesions with dermocorticoids (DC). In case of failure, topical immunomodulators (TI) can be used instead. A daily maintenance treatment with emollients is fundamental to restore the cutaneous barrier. A proactive treatment using DC or TI also prolongs the eczema remissions.

INTRODUCTION
Atopic dermatitis (AD) is one of the most common inflammatory skin disorders. It is characterized by recurring eczema lesions with intense pruritus and skin dryness. It especially affects infants and children, causing changes in their and their families’ quality of life.

I/ EPIDEMIOLOGICAL DATA
AD prevalence is 10-20% in developed countries where the socio-economic level is high ...
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