UV protecting activity of ferulic acid polymeric derivative

FRANCESCO PUOCI1*, GIUSEPPE CIRILLO1, ROCCO SETTINO2, MANUELA CURCIO1, ORTENSIA ILARIA PARISI1, FRANCESCA IEMMA1, UMILE GIANFRANCO SPIZZIRRI1, NEVIO PICCI1
*Corresponding author
1. Università della Calabria, Dipartimento di Scienze Farmaceutiche, Edificio Polifunzionale, Arcavacata di Rende (CS) 87036, Italy
2. Framesi S.p.A., S.S. Dei Giovi, 135, Paderno Dugnano (MI), 20037, Italy

Abstract

In this work, polymeric derivative of ferulic acidwas synthesized by employing ascorbic acid-H2O2 asredox initiator system at room temperature. The insertionof ferulic acid into the polymeric chain was confirmed byFT-IR analyses, and the total antioxidant capacity of themacromolecular system determined by the molybdatemethod, and correspond to a ferulic acid equivalentconcentration of 0.59 mM. UV spectra are characterized bybroad absorption bands in the UVA and UVB region, showingthe efficiency of the polymeric system in preventing theUV-induced damages.


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