Zurko – 3D efficacy evaluation, volume analysis and viscoelastic properties


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Skin aging is a complex biological process influenced by a combination of two main factors; endogenous (genetics, cellular metabolism, hormone and metabolic processes) and exogenous (chronic light exposure, pollution, ionizing radiation, chemicals, toxins). These factors lead together to cumulative structural and physiological alterations and progressive changes in each skin layer as well as changes in skin appearance. Knowing aging skin characteristics will allow us to understand the changes which will be seen at the skin level (1).


The skin components that contribute to the mechanical properties of the skin undergo structural and functional modifications as a consequence of the aging process.


Fibroblasts stiffen, their rate of new component production slows and fibrils, glycosaminoglycans and the number of fibroblasts are reduced. Collagen fragmentation and clumping are also observed in the dermis of aged skin in vivo. As a result, the skin stiffness increases and elasticity decreases.


So, presentation of aging of the entire face is associated with the gravity impact, muscles action, loss of volume, diminishi ...