MARCO FONTANI¹*, MARIAGRAZIA COSTA¹, MARY VIRGINIA ORNA²
*Corresponding author
1. Dipartimento di Chimica “Ugo Schiff”, Università di Firenze, via della Lastruccia, 13 – 50019 Sesto F.no, Firenze, Italy 
2. College of New Rochelle, New Rochelle, New York, USA

Abstract

Guido Pellizzari (1858-1938) was the first of Hugo Schiff’s (1834-1915) students to become university professors. Guido Pellizzari specialized in organic chemistry. The preparation of 1,2,4-triazole derivatives by baking a mixture of an amide and an acyl hydrazide is also referred to as the Pellizzari reaction. This reaction has been applied for the preparation of mono-substituted-, bi-substituted-, and tri-substituted 1,2,4-1H-triazoles.

INTRODUCTION

Professor at the University of Catania and Cagliari, in 1891 Pellizzari occupied the chair of chemistry at the University of Genoa and in 1916 he moved to the “Istituto di Studi Superori Pratici e di Perfezionamento” (later University of Florence) in Florence. Guido Pellizzari performed various researches in the field of organic chemistry. The preparation of 1,2,4-triazoles for dry heating of mixtures of aliphatic amides and hydrazides was named after him. It has been reported that co-heating a mixture of formamide and hydrazine hydrochloride with pulverized KOH can improve the yield of 1,2,4-triazole. This reaction has been applied for the preparation of mono-substituted-, bi-substituted-, and tri-substituted 1,2,4-1H-triazoles.

IN EVERYTHING AND FOR EVERYTHING SIMILAR TO SCHIFF: MISOGYNY AND CHEMISTRY

Guido Pellizzari was the second son of Giorgio Pellizzari (1814-1894), a notable physician, and his wife Adelaide Marzichi Lenzi (d. 1910); he was born in Florence on 30^th October 1858. He attended private lessons until 1871 when he chose to attend the Technical School (Istituto P ...