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Skin aging is a complex process induced by both chronological and environmental factors. Chronological aging is mainly related to a decrease in the turnover rate of the epidermis and the collagen content. In addition to these physiological skin processes, environmental factors such as smoking and air pollution, can act on skin and promote cutaneous aging. Moreover, exposure to UV radiation (photo-aging) can lead to some evident skin changes such as solar lentigines and mottled pigmentation. Even if molecular mechanisms are still not completely understood, these aging factors seem to induce some defensive biological events in the body and the skin that result in the production of radical oxygen species (ROS) and oxidative stress status. In the last decade, several studies were carried out on antioxidant substance oral intake with the purpose of strength ...