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Mushroom proteins Potential therapeutic agents

EVA GUILLAMÓN1*, ANA GARCÍA-LAFUENTE1, MIGUEL LOZANO1, CARLOS MORO1, IRENE PALACIOS1, M. D’ARRIGO1, J.A. MARTÍNEZ2, ANA VILLARES1
*Corresponding author
1. Centro para la Calidad de los Alimentos Instituto Nacional de Investigación y Tecnología Agraria y Alimentaria (INIA) Campus Duques de Soria, c/ José Tudela s/n, Soria, 42004, Spain
2. Universidad de Navarra, Dpto. de Fisiología y Nutrición Edificio de Investigación, c/ Irunlarrea 1, Pamplona, 31008, Spain

Abstract

During the last decades the potential role of mushroom proteins in the prevention and treatment of human health have attracted the interest of the scientific community. This short review focuses on the nutritional value and mainly,the biological effects of proteins isolated from edible mushrooms. Mushrooms are rich in protein with high biological quality.They include ribosome inactivating proteins, lectins, antifungal proteins, ubiquitin-like proteins, protease inhibitors, ribonucleases, laccases, and other enzymes. The bioactive protein may display a great variety of important biological activities such as antifungal, antimicrobial, antiviral, antiproliferative, antimitogenic, immunomodulatory and hypotensive effects. Therefore, some of mushroom proteins with potent valuable properties have been isolated and their potential usesas therapeutic agents against human diseases have been studied.


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