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New vistas in mass spectrometry for sequence analysis of natural and synthetic biodegradable macromolecules

MAREK KOWALCZUK
School of Biology, Chemistry and Forensic Science, Faculty of Science and Engineering,

University of  Wolverhampton, Wolverhampton, WV1 1SB, United Kingdom

KEYWORDS: Biodegradable polymers, PHA, mass spectrometry, sequencing.
ABSTRACT:
Biodegradable polymers have become materials of hope for the future and knowledge on the relationships between their structure, properties and function is essential for prospective safe applications of such materials in the areas of human health and the environment. Examples are given of the uses of mass spectrometry (MS) for structural studies of biodegradable (co)polymers along with the use of multi-stage electrospray mass spectrometry (ESI-MSn). Specifically they concern applications of MS forthe characterization of natural biodegradable polymers and their derivatives, ESI-MSn in the synthesis of biodegradable copolyesters, MS for forensic engineering of advanced biodegradable polymeric materials as well as ESI-MSn for identification of selected biodegradable polymers on the way of molecular labelling.


INTRODUCTION

Biodegradable polymers play an important role in human life, increasingly becoming having an irreplaceable role. This concerns in particular medi ...
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