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Hepatoprotective activities of green tea in nonalcoholic fatty liver disease

HEA JIN PARK, RICHARD S. BRUNO*
*Corresponding author
University of Connecticut, Department of Nutritional Sciences, Storrs, CT 06269-4017, USA

Abstract

Nonalcoholic fatty liver disease (NAFLD) is a constellation of asymptomatic liver diseases that increase liverrelatedmorbidity and mortality risk. The development of NAFLD is attributed to obesity and insulin resistance that causeexcess hepatic lipid accumulation and increase the vulnerability of the liver to hepatotoxic insults such as oxidative stressand inflammatory responses. Accumulating evidence demonstrates that green tea, likely through its catechins, exertshypolipidemic, antioxidant and anti-inflammatory activities, making it an ideal candidate functional food for preventingand/or managing NAFLD. Thus, this review will describe the multi-faceted hepatoprotective activities of green tea on thepathogenic events leading to NAFLD.



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